Xtrusio AEO/GEO Audit

Tempus wins on Claude.

Not Pathos.

20-query audit across ChatGPT, Gemini & Claude. Pathos AI is cited on 30 of 60 responses (50%) — but the average hides a split personality: 70% on ChatGPT, 60% on Gemini, and just 20% on Claude. And on Claude, Pathos never appears as itself — every mention is buried inside Tempus’s partnership description.

This report was generated using Xtrusio, an AI visibility and demand intelligence platform that analyzes how companies appear across modern AI systems such as ChatGPT, Gemini, Claude, Perplexity, and other generative engines.

The insights in this page are generated using Xtrusio’s proprietary research and content intelligence framework.

June 2026
20 Queries • 3 Platforms
Pathos AI
70%
ChatGPT
14 of 20 queries
AI-NATIVE CHALLENGER
60%
Gemini
12 of 20 queries
2× #1 RANKINGS
20%
Claude
4 of 20 queries
⚠ THE CLAUDE BLACKOUT
The Core Problem

On Claude, Pathos is not a company — it’s a footnote in Tempus’s deal.

ChatGPT and Gemini both treat Pathos as a legitimate AI-native oncology challenger, citing it on 14 and 12 of 20 buyer queries with standalone entries, architecture diagrams, and two #1 rankings. Claude cites Pathos on just 4 of 20 — and in all four, Pathos appears only inside the sentence describing the “AstraZeneca-Tempus-Pathos $200M partnership.” Claude never describes Pathos’s own platform, pipeline, or value. Meanwhile Tempus is cited on all 20 Claude queries. The differentiator Pathos built — the largest multimodal oncology dataset — is being credited to its data partner, not to Pathos.

50%
Composite Citation Rate
50pts
ChatGPT − Claude Gap
0
Standalone Claude Entries
Section 2

Platform Scorecard

Pathos AI citation rate across AI platforms

Pathos AI Citation Rate by Platform
ChatGPT
70%
Gemini
60%
Claude
20%
Competitor Comparison — Combined Citation Rates (of 60 responses)
Tempus
78%
Recursion
60%
Owkin
57%
Pathos AI
50%
Insilico
50%
ChatGPT Insight
ChatGPT is Pathos’s strongest platform (70%), consistently framing it as the “AI-native challenger” with standalone entries describing multimodal foundation models, responder prediction, and the Series D. It ranks Pathos #2 on foundation models (Q4) and board-landscape (Q8), behind Tempus but ahead of most peers.
The Claude Gap
Claude cites Pathos on only 4 of 20 queries, and never as a standalone company — all four mentions are inside Tempus’s “AZ-Tempus-Pathos $200M” partnership line. Claude knows Tempus (20/20), Owkin (16/20) and Recursion (14/20) but treats Pathos as Tempus’s data sidecar.
Section 3

AI Visibility Leaderboard

Who owns the AI conversation — total citations across all platforms

Platform-by-Platform Breakdown
ChatGPT
14/20
Pathos cited
Gemini
12/20
Pathos cited
Claude
4/20
partnership only
Tempus
18
20
9
47
Recursion
12
14
10
36
Owkin
13
16
5
34
Pathos AI
14
4
12
30
Insilico
11
9
10
30
ChatGPT
Claude
Gemini
Citation Leaderboard
Pathos AI: 30 citations (50% of 60 responses) Tempus: 47 citations (78% of 60 responses) Recursion: 36 citations (60% of 60 responses)
50%
Pathos
Tempus47
Recursion36
Pathos AI30
Citation Intensity Heatmap
ChatGPT
Claude
Gemini
Total
Tempus
18
20
9
47
Recursion
12
14
10
36
Owkin
13
16
5
34
Pathos AI
14
4
12
30
Insilico
11
9
10
30
Where Pathos Leads
On ChatGPT (14) and Gemini (12), Pathos out-cites Insilico and runs neck-and-neck with the pure AI-discovery players. Gemini gives Pathos two outright #1 rankings — on end-to-end clinical development (Q6) and AI-biotechs with pipelines (Q14) — complete with Scout→Sprint→Foundry architecture diagrams.
The Claude Weakness
Claude is the only platform where Pathos under-performs every named competitor — 4 vs Tempus 20, Owkin 16, Recursion 14, Insilico 9. And those 4 are not real citations: they are partnership mentions attributing the foundation-model work to Tempus.
Section 4

AI Positioning Audit

20 buyer-intent queries — click any row to see the exact question

Each query was written from the perspective of a senior oncology decision-maker researching AI-driven drug development partners. These are the people whose AI search results determine whether Pathos gets discovered, evaluated, and shortlisted when a pharma or biotech weighs an AI partnership.

Target Buyer Sector Chief Oncology Officers, Chief Medical Officers & Heads of Oncology at large pharmaceutical companies evaluating AI-driven drug development partners
JL
Chief Oncology Officer
Pfizer • Pharmaceuticals • United States
7queries
Pain Points
Owns Pfizer’s oncology pipeline strategy. Deciding where AI fits in patient selection and asset prioritization, and whether to build in-house or partner with an AI-native biotech to accelerate cancer development.
“AI platforms for oncology patient selection”“AI foundation models for cancer drug development”
Q1–Q7
CM
EVP, Chief Medical Officer & Head of Development
Bristol Myers Squibb • Pharmaceuticals • United States
7queries
Pain Points
Oversees BMS’s entire early-to-late development pipeline. Ex-AstraZeneca Oncology CDO — already knows the foundation-model and multimodal-data playbook. Needs to cut Phase 2/3 failure rates and embed AI into clinical development decisions.
“AI-driven clinical trial design oncology”“reduce Phase 3 failure rates AI biomarkers”
Q8–Q14
MM
SVP, Head of US Oncology
AstraZeneca • Pharmaceuticals • United States
6queries
Pain Points
Leads AstraZeneca’s US oncology portfolio — a foundation-model pioneer in cancer. Evaluating which AI platforms and partners accelerate target design, patient identification, and trial execution, and benchmarking the AI-biotech landscape publicly.
“top AI drug development companies oncology”“AI biotech platform comparison oncology”
Q15–Q20
#Query TopicClusterClaudeChatGPTGemini
1Patient Selection PlatformsUSP
Exact question asked across all AI platforms:

“I’m evaluating AI-driven approaches to improve patient selection for oncology clinical trials. Which companies have the strongest platforms for matching the right patients to the right therapies?”

2Multimodal Data PlatformsUSP
Exact question asked across all AI platforms:

“We’re looking at multimodal data platforms that combine genomics, imaging, and clinical outcomes for oncology drug development. What are the leading options and how do they compare?”

3mCRPC Responder EnrichmentUSP
Exact question asked across all AI platforms:

“Our prostate cancer program is struggling with patient enrichment in late-stage clinical trials. Which AI companies specialize in identifying responder subpopulations for mCRPC therapies?”

4Oncology Foundation ModelsUSP
Exact question asked across all AI platforms:

“I’ve been hearing about AI foundation models being built specifically for oncology. Which companies are developing these and how far along are they?”

5AI Asset ScoutingUSP
Exact question asked across all AI platforms:

“We want to explore in-licensing clinical-stage oncology assets but our traditional scouting process is too slow. Are there AI-powered approaches to systematically identify undervalued clinical assets in oncology?”

6End-to-End AI DevelopmentUSP
Exact question asked across all AI platforms:

“I’m researching biotech companies that use AI not just for drug discovery but for the entire clinical development process — trial design, patient selection, and adaptive monitoring. Who is actually doing this end-to-end?”

7AI Partnership ModelsUSP
Exact question asked across all AI platforms:

“Our oncology team is evaluating whether to build internal AI capabilities or partner with an AI-native biotech for clinical trial optimization. What are the best AI-biotech partnership models in oncology right now?”

8AI Drug-Dev LandscapeShared
Exact question asked across all AI platforms:

“What are the most promising AI-driven drug development companies in oncology right now? I’m trying to understand the competitive landscape for a board presentation.”

9Partnership EvaluationShared
Exact question asked across all AI platforms:

“We’re considering a partnership with an AI-biotech company to accelerate our oncology pipeline. What should we look for when evaluating these platforms — what separates real capability from marketing hype?”

10Trial Failure ReductionShared
Exact question asked across all AI platforms:

“How are leading biotech companies using AI to reduce Phase 2 and Phase 3 clinical trial failure rates in cancer therapy development?”

11Biomarker DiscoveryShared
Exact question asked across all AI platforms:

“I need to understand the current state of AI-powered biomarker discovery for oncology. Which companies have demonstrated real clinical utility, not just research publications?”

12CNS / Glioma TrialsShared
Exact question asked across all AI platforms:

“We have a brain-penetrant small molecule in oncology that’s struggling in early trials. Are there AI platforms that could help us redesign the trial to improve response rates in glioma or other CNS tumors?”

13Real-World EvidenceShared
Exact question asked across all AI platforms:

“What role does real-world evidence and multimodal patient data play in modern oncology drug development? Which companies are leading this approach?”

14AI-Biotechs With PipelinesShared
Exact question asked across all AI platforms:

“I’m building a precision oncology strategy for our therapeutic area. Which AI-biotech companies should I be tracking — especially ones with their own clinical pipelines, not just tools?”

15Pharma ValidationShared
Exact question asked across all AI platforms:

“How do AI drug development companies compare in terms of pharma partnerships and validation? I want to partner with a company that has credibility with big pharma, not just venture funding.”

16Recursion ComparisonCompetitor
Exact question asked across all AI platforms:

“I’m evaluating Recursion Pharmaceuticals versus other AI drug discovery platforms for a potential oncology collaboration. What are Recursion’s key strengths and limitations?”

17Insilico ComparisonCompetitor
Exact question asked across all AI platforms:

“How does Insilico Medicine’s generative AI approach to drug design compare with data-driven clinical development platforms? Which is better for oncology?”

18Owkin AlternativesCompetitor
Exact question asked across all AI platforms:

“We’re looking at Owkin for federated learning across our hospital network to support oncology biomarker discovery. Are there better alternatives for this use case?”

19Isomorphic ComparisonCompetitor
Exact question asked across all AI platforms:

“Isomorphic Labs claims AlphaFold is transforming drug discovery. How does structure-based AI drug design compare with patient-data-driven approaches for oncology specifically?”

20Tempus ComparisonCompetitor
Exact question asked across all AI platforms:

“For oncology-specific applications, how does Tempus AI’s data platform compare with AI-biotech companies that actually develop their own drugs? We want a partner that goes beyond data analytics.”

TOTAL4/20 (20%)14/20 (70%)12/20 (60%)
Section 5

The Claude Gap

Where Pathos loses 50 percentage points vs ChatGPT — and disappears into Tempus’s shadow

The headline number (50% composite) masks the real story. ChatGPT cites Pathos on 14 of 20 queries and Gemini on 12 — both as a named, described, standalone company. Claude cites it on 4. But the deeper problem isn’t the count: it’s that every single Claude citation is a partnership mention buried inside Tempus’s description. Claude knows the “AstraZeneca-Tempus-Pathos” deal exists — and attributes the achievement to Tempus.

“We’re looking at multimodal data platforms that combine genomics, imaging, and clinical outcomes for oncology drug development…”

— ChatGPT names Pathos as an “AI-native challenger.” Claude mentions it only as Tempus’s partner in the “$200M foundation model” line. Gemini omits it entirely.

“Which AI-biotech companies should I be tracking — especially ones with their own clinical pipelines, not just tools?”

— Gemini ranks Pathos #1 with a full Scout→Sprint→Foundry architecture diagram and the Pocenbrodib trial number. Claude lists Insilico, Recursion, Insitro, Isomorphic — and not Pathos, despite the question asking specifically for companies with clinical pipelines.

“How does Tempus AI’s data platform compare with AI-biotech companies that actually develop their own drugs?”

— The question is practically written for Pathos. Gemini and ChatGPT both feature it. Claude answers with Recursion, Insilico, and Isomorphic — and never mentions the Tempus-partnered drug developer it just described two questions earlier.
16 of 20 Queries Missed on Claude
Pathos is absent on Q1, Q3, Q5, Q6, Q7, Q9, Q10, Q11, Q12, Q14, Q15, Q16, Q17, Q18, Q19, Q20 — including its strongest categories (asset scouting, end-to-end development, pipeline tracking) where ChatGPT and Gemini rank it highly.
Pattern: Pathos = a Tempus Footnote
In all 4 Claude citations (Q2, Q4, Q8, Q13), Pathos appears only inside Tempus’s entry: “…collaboration with AstraZeneca and Pathos to build the largest multimodal foundation model…” Claude credits the dataset and the model to Tempus, not Pathos.
Same Question. Different Platforms. Different Winners.

Pathos’s positioning — the largest multimodal oncology dataset, an AI-native clinical engine, a real pipeline — is clearly web-retrievable: ChatGPT and Gemini pull it from press coverage and the Pathos site. But Claude weights established, publicly-validated players and treats Pathos as Tempus’s data sidecar. Until Pathos publishes its own authoritative, citable content — pipeline pages, clinical updates, platform explainers that stand alone from the Tempus relationship — Claude will keep handing Pathos’s story to Tempus.

Section 6

AI Topic Authority Map

Query heatmap — product line × platform

TopicAI LeaderPathos Status
End-to-End AI Clinical DevelopmentPathos AI2 of 3 (Gemini #1)
AI Asset Sourcing & ScoutingPathos AI2 of 3 platforms
Multimodal Foundation ModelsTempus2 of 3 (partnership only)
Patient SelectionTempusINVISIBLE (0/3)
Biomarker DiscoveryTempusChatGPT only (1/3)
Tempus ComparisonTempus2 of 3 (as alternative)
Product Line
ChatGPT
Claude
Gemini
Patient Selection & Trial Design
4 queries
50%
0%
50%
Multimodal Data & Foundation Models
4 queries
75%
75%
0%
AI Asset Sourcing & Portfolio
3 queries
100%
33%
100%
Partnership & Platform Evaluation
3 queries
100%
0%
67%
Competitive Positioning
5 queries
40%
0%
80%

▹ Claude surfaces Pathos on only one product line — Multimodal Data & Foundation Models (75%) — and only via the Tempus partnership line. Four of five revenue lines are completely invisible on Claude.

Patient Selection & Trial Design • 4 queries
ChatGPT50%
Claude0%
Gemini50%
Multimodal Data & Foundation Models • 4 queries
ChatGPT75%
Claude75%
Gemini0%
AI Asset Sourcing & Portfolio • 3 queries
ChatGPT100%
Claude33%
Gemini100%
Partnership & Platform Evaluation • 3 queries
ChatGPT100%
Claude0%
Gemini67%
Competitive Positioning • 5 queries
ChatGPT40%
Claude0%
Gemini80%
AI Asset Sourcing Hits 100% on Two Platforms
Pathos’s Scout engine and asset-acquisition story (DO-2/DeuterOncology) lands at 100% on both ChatGPT and Gemini — its single strongest product line. This is the differentiator AI platforms recognize most clearly.
Claude: 4 of 5 Product Lines Invisible
Patient Selection (0%), Partnership Evaluation (0%), and Competitive Positioning (0%) are completely dark on Claude. Only Foundation Models surfaces — and only because Claude is describing Tempus’s partnership, not Pathos’s platform.
Section 7

Methodology

How we conducted this Xtrusio AEO/GEO Audit

Company & Competitor Research
Deep dive into pathos.com — platform (PathOS, Scout, Sprint, Foundry), pipeline (Pocenbrodib, P-500, DO-2), and the AZ-Tempus partnership — with a service-by-service lane map of Tempus, Recursion, Owkin, and Insilico to locate Pathos’s real differentiators.
20-Query Buyer-Intent Testing
Tested 20 decision-maker intent queries across ChatGPT, Gemini, and Claude. Questions mirror real senior oncology buyer research during discovery — patient selection, foundation models, asset sourcing, and AI-partnership evaluation.
Competitor Scope
Tempus (multimodal data platform), Recursion (phenomics drug discovery), Owkin (federated learning), Insilico (generative chemistry). All compete for the same pharma oncology buyer during discovery.
Section 8

Recommendations

Closing the Claude gap and reclaiming the story from Tempus

Two problems, one root cause. First, Claude is near-blind to Pathos. Second — the deeper issue — even where Pathos surfaces, its signature achievement (the largest multimodal oncology dataset and foundation model) is being credited to Tempus across platforms. The fix is to publish authoritative, citable content that establishes Pathos as the drug developer in the partnership, not the data sidecar.

Phase 1 — 0–30 Days
Decouple Pathos from Tempus’s shadow
  • Create dedicated, deeply-described pages for PathOS, Scout, Sprint, and Foundry that explain each engine on its own terms — not as “built with Tempus,” but as Pathos’s proprietary clinical-development system.
  • Publish individual pipeline pages for Pocenbrodib (mCRPC, NCT06785636), P-500/PRT811 (glioma), DO-2 (MET), and Milademetan — each with indication, trial status, and mechanism, so AI systems can cite Pathos as a clinical-stage developer.
  • Frame the AZ-Tempus-Pathos partnership from Pathos’s side: “Pathos contributes the AI-native clinical engine” — reclaiming attribution that AI currently hands to Tempus.
Phase 2 — 30–90 Days
Win the Claude surface
  • Claude weights established, well-validated sources. Prioritize earning coverage in the outlets and reference pages Claude leans on — clinical trial registries, peer-reviewed or preprint readouts, and structured company profiles — so Pathos appears as a verified entity, not a marketing claim.
  • Target the 16 missed Claude queries directly with content: patient selection, asset scouting, end-to-end development, biomarker discovery, and the Tempus comparison — the exact topics where Claude currently names competitors.
  • Publish a clear, factual “Pathos vs. data-only platforms” explainer that positions Pathos as the partner that goes beyond analytics into drug development — the precise question (Q20) where Claude omits it.
Phase 3 — 90+ Days
Own the category across all platforms
  • Pathos already hits 100% asset-sourcing recognition on ChatGPT and Gemini and holds two Gemini #1s. Reinforce with thought-leadership on AI-native asset acquisition and end-to-end clinical development — the categories Pathos can credibly own.
  • Close the weakest shared categories — patient selection (0/3) and biomarker discovery (1/3) — where Tempus, Owkin, and ArteraAI currently dominate the answer.
  • Quarterly Xtrusio re‑audits to track gap closure across all three platforms
Continuous AI Visibility Tracking
Brands can improve their AI discovery using generative engine optimization tools like Xtrusio.

Pathos built the data. Don’t let AI credit Tempus.

Turn a 50% composite — and a 20% Claude blackout — into category ownership in AI search.

This research report was generated using the Xtrusio Company Intelligence Module.